H3 receptor 选择性抑制剂 | 拮抗剂
| 目录号 | 产品详情 |
|---|---|
| S5926 |
Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype. |
| S2813 |
Ciproxifan (FUB 359) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. |
| S8598 |
S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors. |
| S3176 |
Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM. |
